River Thames Run is the sixth Checkpoint race in London. If the races are played in the correct order, getting a place on the podium (Amateur) or winning it (Professional) will unlock the Panoz GTR-1 and its four skins. The race starts at the north of the city and heads to St. Paul's Cathedral. You can use an alleyway or one-way road to reach the road near River Thames. The race then heads to the Houses of Parliament, where the finish line is (though with London Mod 1, the routes of some opponents may be blocked by trees). The opponents include three VW New Beetles, two Ford F-350s and two Light Tactical Vehicles (Amateur) or three VW New Beetle RSis and four Aston Martin DB7 Vantages (Professional).

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